Figure 1

Chronic Obstructive Pulmonary Disease and Lung Cancer

Common Pathogenesis, Shared Clinical Challenges Bartolome R. Celli1 1Pulmonary and Critical Care Division, Brigham and Women’s Hospital, Harvard Medical School, Boston, Massachusetts   (Received in original form July 9, 2011; accepted in final form October 6, 2011) Correspondence and requests for reprints should be addressed to Bartolome R. Celli, M.D., 75 Francis Street, Boston, MA / прочети повече

Figure 1. The Alair bronchial thermoplasty system.

Bronchial Thermoplasty for Severe Asthma

Momen M. Wahidi1 and Monica Kraft1 1Division of Allergy, Pulmonary, and Critical Care Medicine, Department of Medicine, Duke University Medical Center, Durham, North Carolina   (Received in original form May 20, 2011; accepted in final form October 21, 2011) Author Contributions: Both authors have contributed to the review of data and writing of this manuscript. / прочети повече


Impact of Anxiety and Depression on Chronic Obstructive Pulmonary Disease Exacerbation Risk

Catherine Laurin1,2,3,4*, Gre´gory Moullec1,2,4*, Simon L. Bacon1,2,3,4, and Kim L. Lavoie1,2,3,5   1Montreal Behavioural Medicine Centre, Montreal, Quebec, Canada; 2Research Centre, Hoˆpital du Sacre´-Coeur de Montre´al, Montreal, Quebec, Canada; 3Research Centre, Montreal Heart Institute, Montreal, Quebec, Canada; 4Department of Exercise Science, Concordia University, Montreal, Quebec, Canada; and 5Department of Psychology, Universite´ du Que´bec a` Montre´al, / прочети повече

Building a Better Physician — The Case for the New MCAT

The NEW ENGLAND JOURNAL of MEDICINE april 5, 2012   The Medical College Admission Test (MCAT), a prerequisite for admission to U.S. medical schools, currently consists of four sections: physical sciences, verbal reasoning, a writing sample, and biologic sciences. A 2004 Institute of Medicine report on “Improving Medical Education” and several years of evaluation identified / прочети повече

Westermark S ign in Pulmonary Embolism

Признак на WESTERMARK при белодробна емболия – Westermark Sign in Pulmonary Embolism

Westermark Sign in Pulmonary Embolism Anant Subramanian Krishnan, M.D. Tristan Barrett, M.D. Addenbrooke’s Hospital Cambridge, United Kingdom A 47-year-old woman presented to the emergency department with acute shortness of breath and hypoxemia. Her medical history included sex reassignment, for which she was taking estrogen, and a deep-vein thrombosis on the left side, for which she / прочети повече


Treatment of Tuberculosis

SUMMARY Responsibility for Successful Treatment The overall goals for treatment of tuberculosis are (1) to cure the individual patient, and (2) to minimize the transmission of Mycobacterium tuberculosis to other persons. Thus, successful treatment of tuberculosis has benefits both for the individual patient and the community in which the patient resides. For this reason the / прочети повече

FIGURE 1. Mean pulmonary artery pressure (P¯pa) in a hospital-based cohort of 998 chronic obstructive pulmonary disease (COPD) patients with a mild to very severe airflow limitation.

Pulmonary hypertension in COPD

ABSTRACT: Mild-to-moderate pulmonary hypertension is a common complication of chronic obstructive pulmonary disease (COPD); such a complication is associated with increased risks of exacerbation and decreased survival. Pulmonary hypertension usually worsens during exercise, sleep and exacerbation. Pulmonary vascular remodelling in COPD is the main cause of increase in pulmonary artery pressure and is thought to / прочети повече

FIGURE 1. Definition of a morbidity/mortality event: primary end-point used in the SERAPHIN trial.

Looking to the future: a new decade of pulmonary arterial hypertension therapy

ABSTRACT: Pulmonary arterial hypertension (PAH) is a severe and debilitating disease characterised by vascular proliferation and remodelling of the small pulmonary arteries, leading to a progressive increase in pulmonary vascular resistance, increased afterload on the right ventricle and, ultimately, right heart failure. Although there is no ‘‘cure’’ for PAH, the availability of targeted therapies over / прочети повече


Emphysema — A Disease of Small Airways or Lung Parenchyma?

In 1984, the Division of Lung Diseases at the National Heart, Lung, and Blood Institute funded a workshop that led to what is still the basis for most definitions of emphysema: “a condition of the lung characterized by abnormal, permanent enlargement of airspaces distal to the terminal bronchiole, accompanied by the destruction of their walls, / прочети повече

Table 1. Characteristics of the 78 Patients and Controls.*

Small-Airway Obstruction and Emphysema in Chronic Obstructive Pulmonary Disease

Abstract Background The major sites of obstruction in chronic obstructive pulmonary disease (COPD) are small airways (<2 mm in diameter). We wanted to determine whether there was a relationship between small-airway obstruction and emphysematous destruction in COPD. Methods We used multidetector computed tomography (CT) to compare the number of airways measuring 2.0 to 2.5 mm / прочети повече